Scientists investigate the evolutionary origin of SARS-CoV-2 using recombination-aware phylogenetic analysis

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe acute respiratory syndrome coronavirus (SARS-CoV) are members of the subgenus Sarbecovirus, whose genomic length is around 30,000 base pairs. These viruses encode four structural proteins, namely spike (S), envelope (E), membrane (M), and nucleocapsid (N). Study: Recombination-aware phylogenetic analysis sheds light on the evolutionary origin of … Read more

The potential of Sofosbuvir against COVID-19 neurological symptoms

On 11th March 2020, the World Health Organization (WHO) announced the global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the coronavirus disease 2019 (COVID-19). Despite the discovery of effective COVID-19 vaccines and the subsequent commencement of vaccination programs globally, SARS-CoV-2 infections have been widely reported due to the emergence of new … Read more

Scientists explore bat sarbecovirus isolation in Japan

In a recent study published in Emerging Infectious Diseasesresearchers performed bat sarbecovirus isolation experiments using Rhinolophus cornutus bats from several regions in Japan that were phylogenetically situated in the same cluster of viruses related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Isolation of Bat Sarbecoviruses, Japan. Image Credit: Independent birds/Shutterstock Highly pathogenic human … Read more

How gut microbes influence immune response to SARS-CoV-2

An article published in Critical Reviews in Food Science and Nutrition journal provides an overview of the role of gut microbiota in shaping the host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Gut microbiome and anti-viral immunity in COVID-19. Image Credit: Design_Cells/Shutterstock Background SARS-CoV-2, the causative pathogen of the coronavirus disease … Read more