Treatment to boost white blood cells may benefit patients with glioblastoma

A new study led by Washington University School of Medicine in St. Louis reveals at least one cause of low white blood cell counts in patients treated for glioblastoma and demonstrates a potential treatment strategy that improves survival in mice. Shown are MRI scans of a patient with this type of brain tumor. Patients with … Read more

UK oncologists and cardiologists collaborate to prevent chemo-induced cardiomyopathy in cancer patients

Ever since she was 12 years old, Barbie Johnson has been a Kentucky girl at heart. Raised in the bluegrass, Barbie has worked at UK HealthCare for 18 years, first in gynecologic oncology and now in surgery scheduling. But she had no idea that while working with patients she would eventually become one herself. In … Read more

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Scientists at the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs). These findings from Sylvester’s Myeloma Research Institute highlight the importance of fully understanding the long-term impact anti-cancer … Read more

Pembrolizumab offers a major added survival benefit for patients with advanced cervical cancer

Pembrolizumab has recently been approved in combination with chemotherapy for the treatment of women with persistent, recurrent, or metastatic cervical cancer whose tumors express PD-L1. Chemotherapy with or without bevacizumab is possible. The German Institute for Quality and Efficiency in Health Care (IQWiG) has now examined in an early benefit assessment whether pembrolizumab in this … Read more

Routine Tests for Hearing Loss in All Cisplatin-Treated Patients

More than half of patients with testicular cancer treated with first-line cisplatin-based chemotherapy in a recent study developed hearing loss (HL) or tinnitus. Among them, more than a third of those reported clinically significant functional impairment as a result. The findings underscore the need for routine assessment for hearing loss and tinnitus during follow-up of … Read more

Targeting the newly discovered signaling pathway could boost the potency of cancer therapeutics

Cells zealously protect the integrity of their genomes, because damage can lead to cancer or cell death. The genome -; a cell’s complete set of DNA -; is most vulnerable while it is being duplicated before a cell divides. Cancer cells are constantly dividing, so their genomes are constantly in jeopardy. Researchers at Washington University … Read more

Chemotherapy before surgery cuts the risk of colon cancer relapse: Study | Health

According to the results of a Cancer Research UK-funded clinical trial, giving colon cancer patients chemotherapy before surgery cuts their risk of the disease coming back. The FOxTROT trial showed that giving colon cancer patients chemotherapy before rather than after surgery reduced the chance of cancer returning within 2 years by 28 percent. A total … Read more

Preventing Infections in Cancer Patients at Home

Information for health care workers and patients to protect patients from infections. Health care providers should make sure their patients know these guidelines to protect against infectious diseases while their immune systems are low. Hand Hygiene: Patients should wash their hands often with soap and warm water. They should carry alcohol-based hand sanitizer to clean … Read more

Blood Test 24 Hours After Starting Chemo Predicts AML Survival

Examining protein changes in peripheral blood cells just 24 hours after initiating chemotherapy for acute myeloid leukemia (AML) could predict 5-year overall survival, potentially allowing treatment to be changed, say Norwegian researchers. They studied peripheral blood samples from patients with AML and healthy controls, finding that there were several clusters of cells that were different … Read more

New molecular pathway critical to the initiation of pancreatic tumors discovered

Researchers at the University of California San Diego School of Medicine have discovered a molecular pathway critical to the initiation of pancreatic tumors. The mechanism could also contribute to the disease’s high resistance to chemotherapy and its propensity for metastasis. The study, published on January 16, 2022 in Nature Cell Biology, found that pancreatic tumor-initiating … Read more