Scientists investigate the evolutionary origin of SARS-CoV-2 using recombination-aware phylogenetic analysis

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe acute respiratory syndrome coronavirus (SARS-CoV) are members of the subgenus Sarbecovirus, whose genomic length is around 30,000 base pairs. These viruses encode four structural proteins, namely spike (S), envelope (E), membrane (M), and nucleocapsid (N). Study: Recombination-aware phylogenetic analysis sheds light on the evolutionary origin of … Read more

The potential of Sofosbuvir against COVID-19 neurological symptoms

On 11th March 2020, the World Health Organization (WHO) announced the global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the coronavirus disease 2019 (COVID-19). Despite the discovery of effective COVID-19 vaccines and the subsequent commencement of vaccination programs globally, SARS-CoV-2 infections have been widely reported due to the emergence of new … Read more

BW.1- a new Omicron subvariant that escapes immunity

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of the coronavirus disease 2019 (COVID-19), continues to evolve through genomic mutations. Emerging SARS-CoV-2 variants have been categorized as variants of interest (VOI) and variants of concern (VOC) based on their infectiousness, virulence, and capacity to evade immune responses induced through both natural infection … Read more

Intermediate levels of indoor relative humidity have been shown to improve COVID-19 outcomes globally

In a recent study published in the Journal of the Royal Societyresearchers found that indoor relative humidity (RH) modulates the severity of coronavirus disease 2019 (COVID-19) outbreaks, and intermediate RHs between 40 to 60% are robustly associated with better COVID-19 outcomes. Study: Associations between indoor relative humidity and global COVID-19 outcomes. Image Credit: Nhemz/Shutterstock Background … Read more

How gut microbes influence immune response to SARS-CoV-2

An article published in Critical Reviews in Food Science and Nutrition journal provides an overview of the role of gut microbiota in shaping the host immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Gut microbiome and anti-viral immunity in COVID-19. Image Credit: Design_Cells/Shutterstock Background SARS-CoV-2, the causative pathogen of the coronavirus disease … Read more

COVID-19 carries a much higher risk of epilepsy and seizures than influenza

After retrospectively analyzing the data of over 300,000 people, researchers in a recent Neurology journal paper report that a diagnosis of the coronavirus disease 2019 (COVID-19) was associated with a greater risk of both seizures and epilepsy as compared to those diagnosed with influenza infection. Study: Incidence of Epilepsy and Seizures Over the First 6 … Read more