Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Scientists are harnessing a new way to turn cancer cells into potent, anti-cancer agents. In the latest work from the lab of Khalid Shah, MS, PhD, at Brigham and Women’s Hospitala founding member of the Mass. General Brigham healthcare system, investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term … Read more

Serotonin can potentially accelerate degenerative mitral regurgitation, study says

Serotonin can impact the mitral valve of the heart and potentially accelerate a cardiac condition known as degenerative mitral regurgitation, according to a new study led by researchers at Columbia University’s Department of Surgery in collaboration with the Pediatric Heart Valve Center at Children’s Hospital of Philadelphia (CHOP ), the University of Pennsylvania, and the … Read more

Staff shortages at leading Peter MacCallum Cancer Center prompt surgery delays

Patients at Victoria’s leading cancer hospital could have potentially life-changing surgeries delayed due to staff shortages. Key points: About 10 percent of surgeries at the Peter MacCallum Cancer Center could be postponed during February The hospital says the most urgent procedures will be prioritized The AMA’s vice-president says delays across the state can cause significant … Read more

International students asked to pay up-front before emergency treatment in Queensland hospitals

International students have recalled frightening and stressful experiences of being asked to pay hundreds of dollars up-front before being treated in emergency departments at Queensland public hospitals. It has prompted advocates to call for a change to hospital policy to bill students’ health insurance directly. Key points: International students are ineligible for Medicare but are … Read more

Treatment to boost white blood cells may benefit patients with glioblastoma

A new study led by Washington University School of Medicine in St. Louis reveals at least one cause of low white blood cell counts in patients treated for glioblastoma and demonstrates a potential treatment strategy that improves survival in mice. Shown are MRI scans of a patient with this type of brain tumor. Patients with … Read more

Chemotherapy in the afternoon proved to be effective for female lymphoma patients

Chemotherapy is a commonly used regimen for cancer treatment, but it is also a double-edged sword. While the drugs are highly effective at killing cancer cells, they are also notorious for killing healthy cells in the body. As such, minimizing the drug’s damage to the patient’s body is necessary for improving the prognosis of chemotherapy. … Read more

Research offers hope for patients affected by rare, hereditary metabolic diseases

New research offers potential benefits for those affected by the hereditary metabolic disease methylmalonic aciduria. By combining the results of multiple molecular analyses, scientists can better diagnose this rare and severe disease. In the future, an improved understanding of the disease might also improve treatment options. Methylmalonic aciduria (MMA) is a metabolic disorder that affects … Read more

PLK1-mTOR axis may be a promising therapeutic target for sepsis, study suggests

Sepsis, one of the most acute and serious disease complications in the intensive care unit, is caused by various infections and results in life-threatening organ dysfunction. The intestinal barrier plays a vital role in the process of sepsis, and its disruption exacerbates sepsis. A new study in The American Journal of Pathology, published by Elsevier, … Read more

Scientists use next-generation protein degradation technology to study CTCF’s role in transcription

CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children’s Research Hospital used a next-generation protein degradation technology to study CTCF. Their work revealed the superiority of the approach in addition to providing functional insights into how CTCF regulates transcription. The study, published … Read more

Researchers solve an 80-year-old medical mystery that causes kidney damage in children

Researchers at the University of East Anglia have solved an 80-year-old medical mystery that causes kidney damage in children and can be fatal in babies. Those affected by the condition cannot metabolize vitamin D properly, causing a build-up of calcium in the blood and leading to kidney damage and kidney stones. It led to a … Read more