Researchers discover a new function of CRISPR/Cas9 gene scissors

For several years now, the CRISPR/Cas9 gene scissors have been causing a sensation in science and medicine. This new tool of molecular biology has its origins in an ancient bacterial immune system. It protects bacteria from attack by so-called phages, ie viruses that infect bacteria. Researchers from the Institute of Structural Biology at the University … Read more

Scientists investigate the evolutionary origin of SARS-CoV-2 using recombination-aware phylogenetic analysis

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and severe acute respiratory syndrome coronavirus (SARS-CoV) are members of the subgenus Sarbecovirus, whose genomic length is around 30,000 base pairs. These viruses encode four structural proteins, namely spike (S), envelope (E), membrane (M), and nucleocapsid (N). Study: Recombination-aware phylogenetic analysis sheds light on the evolutionary origin of … Read more

The potential of Sofosbuvir against COVID-19 neurological symptoms

On 11th March 2020, the World Health Organization (WHO) announced the global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as the coronavirus disease 2019 (COVID-19). Despite the discovery of effective COVID-19 vaccines and the subsequent commencement of vaccination programs globally, SARS-CoV-2 infections have been widely reported due to the emergence of new … Read more

Scientists explore bat sarbecovirus isolation in Japan

In a recent study published in Emerging Infectious Diseasesresearchers performed bat sarbecovirus isolation experiments using Rhinolophus cornutus bats from several regions in Japan that were phylogenetically situated in the same cluster of viruses related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Isolation of Bat Sarbecoviruses, Japan. Image Credit: Independent birds/Shutterstock Highly pathogenic human … Read more