What was the SARS-CoV-2 seroprevalence among US adults during 2021 to 2022?

In a recent Morbidity and Mortality Weekly Report (MMWR)the United States Center for Disease Control and Prevention (US-CDC) published the preliminary results of the National Health and Nutrition Examination Survey (NHANES) for August 2021–May 2022. Study: SARS-CoV-2 Serology and Self-Reported Infection Among Adults — National Health and Nutrition Examination Survey, United States, August 2021–May 2022. … Read more

What was the SARS-CoV-2 seroprevalence among US adults during 2021 and 2022?

In a recent Morbidity and Mortality Weekly Report (MMWR)the United States Center for Disease Control and Prevention (US-CDC) published the preliminary results of the National Health and Nutrition Examination Survey (NHANES) for August 2021–May 2022. Study: SARS-CoV-2 Serology and Self-Reported Infection Among Adults — National Health and Nutrition Examination Survey, United States, August 2021–May 2022. … Read more

Air pollution-triggered immune surveillance deficits in the lungs increase the risk of respiratory diseases with aging

In a recent research briefing published in Nature Medicineresearchers highlighted the significance of air quality in preserving immune health over the human lifespan, especially lung-related immunity, owing to the lungs’ continuous exposure to the environment. Study: Effect of air pollution on the human immune system. Image Credit: Lemberg Vector studio/Shutterstock Background Aging exacerbates disease susceptibility, … Read more

Machine learning analysis suggests that there are four sub-phenotypes of chronic COVID

In a recent study published in Nature Medicineresearchers identified PASC [post-acute sequelae of coronavirus disease 2019 (COVID-19)] sub-phenotypes depending on conditions diagnosed within 1 to 3 months of acute infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Study: Data-driven identification of post-acute SARS-CoV-2 infection subphenotypes. Image Credit: males_design/Shutterstock Background Studies have examined PASC conditions … Read more

Is remdesivir treatment associated with reduced risk of inpatient mortality among US patients hospitalized with COVID-19?

In a recent study posted to JAMA Network Openresearchers assessed the effect of remdesivir on inpatient coronavirus disease 2019 (COVID-19)-associated mortality among individuals hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in an enormous dataset of United States (US) residents beyond clinical trial settings. Study: Association of Remdesivir Treatment With Mortality Among Hospitalized … Read more

Co-infecting pathogens and the microbiome from SARS-CoV-2 positive and negative samples

In a recent study published in PLOS ONE, researchers evaluated co-infections in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients. Additionally, they explored the differences in microbial profiles of SARS-CoV-2-positive and SARS-CoV-2-negative samples. Study: Evaluation of co-circulating pathogens and microbiome from COVID-19 infections. Image Credit: Kateryna Kon/Shutterstock Background The coronavirus disease 2019 (COVID-19) ruined people’s … Read more

Wearing glasses does not reduce the risk of COVID-19

A new JAMA Network Open study determines the impact of wearing glasses on the risk of infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses. Study: Effect of Wearing Glasses on Risk of Infection With SARS-CoV-2 in the Community A Randomized Clinical Trial. Image Credit: dissx Can eyeglasses prevent infection? … Read more

Study explores histopathological, serological, and clinical characteristics of PASC in patients with mild COVID-19

In a recent study posted to the medRxiv* preprint server, researchers investigated the clinical, histopathological, imaging, and serological characteristics of post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) in patients with mild COVID-19. Study: Clinical, imaging, serological, and histopathological features of pulmonary post-acute sequelae after mild COVID-19 (PASC). Image Credit: Dragana Gordic/Shutterstock Background Long coronavirus … Read more

Immunopeptidome characteristics of human CoV-OC43-infected cells

In a recent study posted to the bioRxiv* preprint server, researchers explored T-cell epitopes derived from human seasonal coronavirus OC43. Study: Immunopeptidome profiling of human coronavirus OC43-infected cells identifies CD4 T cell epitopes specific to seasonal coronaviruses or cross-reactive with SARS-CoV-2. Image Credit: creativeneko/Shutterstock Studies related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and … Read more

How did the seasonal patterns of RSV infections in 2022 compare with those from other COVID-19 pandemic and pre-pandemic years?

In a recent study posted to the medRxiv* preprint server, researchers assessed the impact of the coronavirus disease 2019 (COVID-19) pandemic on the seasonal patterns of RSV (respiratory syncytial virus) infections among young children residing in the US (United States). Study: Disruption in seasonality, patient characteristics and disparities of respiratory syncytial virus infection among young … Read more